This publication aims to inform how global value chain interventions can be more effectively designed, monitored, and evaluated to ensure sustainable inclusion of small- and medium-sized producers. Lessons learned from the MIF’s experience in inclusive business and value chain development interventions in Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua, Paraguay and Peru are complemented by a review of the academic literature on the inclusion of small producers in agro- food chains, and the analysis of successful practices from other development agencies.